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建立简单有效的术中甲状旁腺成像大鼠模型
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JoVE Journal Medicine
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
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建立简单有效的术中甲状旁腺成像大鼠模型

DOI:
10.3791/64222-v

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07:12 min

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August 17, 2022

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, , ,
1Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province,Zhejiang Cancer Hospital, 2The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), 3Institute of Basic Medicine and Cancer (IBMC),Chinese Academy of Sciences

Chapters

  • 00:05Introduction
  • 00:53Animal Preparation
  • 02:05Incision, Dissection of the Subcutaneous Tissue, and Anterior Neck Muscle Fixation
  • 02:56Thyroid Gland Localization and Visual Identification of the Parathyroid Gland (PGs)
  • 04:18Black Iron Oxide Nanoparticles (IONPs) Injection and PGs Identification
  • 05:09Results: Effects of IONP Injection and PGs Identification Post-Injection
  • 05:51Conclusion

Summary

Automatic Translation

Automatic Translation

迄今为止，甲状旁腺（PG）鉴定方法的发展受到临床前研究中缺乏动物模型的限制。在这里，我们建立了一个简单有效的术中PG成像大鼠模型，并使用氧化铁纳米颗粒作为新型PG造影剂来评估其有效性。

Tags

Parathyroid GlandThyroid GlandRat ModelIntraoperative ImagingThyroidectomyIONPSurgical ProcedureAnatomical Landmarks

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