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Journal
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Biology
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结直肠癌原位小鼠模型
JoVE Journal
Biology
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JoVE Journal
Biology
Orthotopic Mouse Model of Colorectal Cancer
Please note that all translations are automatically generated.
Click here for the English version.
结直肠癌原位小鼠模型
DOI:
10.3791/484-v
•
08:43 min
•
December 04, 2007
•
William Tseng
2
,
Xianne Leong
,
Edgar Engleman
1
Department of Surgery
,
University of California, San Francisco – UCSF
,
2
Department of Pathology
,
Stanford University School of Medicine
Chapters
00:00
Title
00:13
Introduction
01:07
Two Techniques for the Orthotopic Mouse Model of Colorectal Cancer
01:50
Instruments
02:49
Mouse Preparation, Laparotomy, and Exposure of Cecum
04:37
Injection of Cells into Cecal Wall
05:07
Transplantation of Tumor onto Cecum
Summary
Automatic Translation
English (Original)
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Automatic Translation
两种技术可用于建立这个模型:一个癌症细胞悬液注入到盲肠壁或一块皮下肿瘤移植到盲肠。这种模式是用于研究大肠癌的自然进程和测试新的治疗药物,对大肠癌的。
Tags
Orthotopic Mouse Model
Colorectal Cancer
Subcutaneous Tumor Model
Cancer Cells
Natural Location
Human Disease
High Fidelity
Techniques
Mouse Anesthesia
Laparotomy
Cecum
Colorectal Cancer Cell Suspension
Single Cell Suspension
Injection
Leakage
Transplantation
Subcutaneous Tumor
Euthanized
Sterile Technique
Tumor Piece
Tumor Cell Infiltration
Primary Tumors
Liver Metastases
Therapeutic Agents
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