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Medicine
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全層軟骨欠損ラットモデルの開発と評価
JoVE Journal
Medicine
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JoVE Journal
Medicine
Development and Evaluation of a Rat Model of Full-Thickness Cartilage Defects
Please note that all translations are automatically generated.
Click here for the English version.
全層軟骨欠損ラットモデルの開発と評価
DOI:
10.3791/64475-v
•
04:34 min
•
May 19, 2023
•
Haiyan Zhang*
1
,
Ronghua Bao*
2
,
Jiaan Xu
,
Yanzhi Ge
,
Zuxiang Chen
,
Mengqiang Fan
,
Guangping Yu
,
Li Zhou
,
Le Guo
,
Letian Shan
,
Hangxing Bao
1
The First Affiliated Hospital
,
Zhejiang Chinese Medical University
,
2
Fuyang Orthopaedics and Traumatology Affiliated Hospital
,
Zhejiang Chinese Medical University
,
3
College of Pharmaceutical Science
,
Zhejiang Chinese Medical University
,
4
Affiliated Zhejiang Hospital
,
Zhejiang University School of Medicine
,
5
Xianju County Hospital of Chinese Medicine
Chapters
00:04
Introduction
01:18
Establishment of Murine Full‐Thickness Cartilage Defects Model
02:27
Measurement of Mechanical Withdrawal Threshold
03:12
Results: Comparative Analysis of Mechanical Withdrawal Threshold in Murine Models
04:10
Conclusion
Summary
Automatic Translation
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Automatic Translation
このプロトコルは、ラットの大腿滑車溝に穴を開け、その後の痛みの行動と組織病理学的変化を測定することにより、全層軟骨欠損(FTCD)モデルを確立します。
Tags
Rat Model
Full-thickness Cartilage Defects
FTCD
Traumatic Cartilage Defects
Post-traumatic Osteoarthritis
Cartilage Injury
Animal Model
Cartilage Defect Evaluation
Mechanical Withdrawal Threshold
Hyperalgesia
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