/
/
Imaging PET/RM non invasivo in un modello murino ortotopico di carcinoma epatocellulare
A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Department of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine,The University of Hong Kong, 2Department of Oncology, MRC Oxford Institute for Radiation Oncology,University of Oxford, 3Department of Surgery, School of Clinical Medicine, HKU-SZH & LKS Faculty of Medicine,The University of Hong Kong, 4Department of Biomedical Engineering,The Chinese University of Hong Kong, 5Department of Diagnostic and Interventional Radiology,Kwong Wah Hospital
Chapters
- 00:04Introduction
- 01:06Subcutaneous Injection of Human Hepatocellular Carcinoma Cell Lines
- 01:45Orthotopic Liver Implantation and Hepatic Artery Ligation
- 04:00[18F] FMISO and [18F] FDG Injection
- 04:42PET/MR Acquisition
- 05:57Results: Effect of Hepatic Artery Ligation on Orthotopic Hepatocellular Carcinoma in Mice
- 07:02Conclusion
Qui, presentiamo un protocollo per creare xenotrapianti di carcinoma epatocellulare ortotopico con e senza legatura dell'arteria epatica ed eseguire la tomografia ad emissione di positroni (PET) non invasiva dell'ipossia tumorale utilizzando [18 F]Fluoromisonidazolo ([18 F]FMISO) e [18 F]Fluorodesossiglucosio ([18F]FDG).
