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Chapters
- 00:05Title
- 02:08Dissection and Cleaning of Arteries
- 03:04Cell Isolation for Patch Clamp Studies
- 04:50Whole-cell Recording to Measure Kv7 Potassium Currents or Membrane Voltage
- 06:36Use of Intact Artery Segments for Pressure Myography
- 09:00Results: Kv7 Potassium Channel Function of Arterial Smooth Muscle using Patch Clamp Electrophysiology and Pressure Myography
- 10:33Conclusion
Medidas do KV7 atividade do canal (KCNQ) de potássio em miócitos isolados arteriais (usando patch braçadeira técnicas eletrofisiológicas) em paralelo com medidas de constritores / dilatador respostas (usando Miografia pressão) pode revelar informações importantes sobre os papéis do KV7 canais em fisiologia do músculo liso vascular e farmacologia.
Tags
Arterial Smooth MuscleKv7 Potassium ChannelPatch Clamp ElectrophysiologyPressure MyographySmooth Muscle CellsResistance ArteriesArtery DiameterBlood FlowSystemic Blood PressureCytosolic Calcium ConcentrationIon TransportersIon ChannelsSignal Transduction PathwaysVasoactive HormonesVasoconstrictionVasodilationTherapeutic AgentsCalcium Channel BlockersKv7 Voltage-activated Potassium ChannelsPhysiological Signal TransductionRat Mesenteric Arteries
