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立体定向颅内植入和<em在体内</em生物发光成像的肿瘤异种移植的小鼠模型系统的多形性胶质母细胞瘤
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JoVE Journal Medicine
Stereotactic Intracranial Implantation and In vivo Bioluminescent Imaging of Tumor Xenografts in a Mouse Model System of Glioblastoma Multiforme
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立体定向颅内植入和<em在体内</em生物发光成像的肿瘤异种移植的小鼠模型系统的多形性胶质母细胞瘤

DOI:
10.3791/4089-v

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10:52 min

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September 25, 2012

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, , , ,
1Department of Radiation Oncology,University of Pennsylvania

Chapters

  • 00:05Title
  • 02:08Orthotopic Xenograft Implantation
  • 07:41Bioluminescent Imaging (BLI) to Monitor Tumor Growth and Response to Therapy
  • 08:38Results: In Vivo Bioluminescent Imaging of Tumor Xenografts in a Mouse Model System of Glioblastoma Multiforme
  • 09:52Conclusion

Summary

Automatic Translation

Automatic Translation

我们描述一个综合性的方法，精确，立体的人多形性胶质母细胞瘤细胞植入到裸鼠的大脑和随后的串行<em在体内</em>成像技术来监测治疗所造成的异种移植物的生长和响应。

Tags

Stereotactic Intracranial ImplantationIn Vivo Bioluminescent ImagingTumor XenograftsMouse Model SystemGlioblastoma MultiformeHigh-grade Primary Brain CancerMedian SurvivalStandard Tri-modality TreatmentSurgical ResectionRadiation TherapyTemozolomide ChemotherapyTherapeutic ApproachesAnimal ModelsTumor GrowthTreatment ResponseBio-imageable GBM Cancer CellsNude MiceAnatomic LocationsIn Vivo Bioluminescent ImagingIntracranial Xenograft GrowthPerioperative MorbidityMortality

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