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Chapters
- 00:05Title
- 01:46Validation of MDA-MB231/5HRE-ODD-luc Cells as a Tool for Measuring Hypoxia Dynamics
- 04:03Culture of MDA-MB231/5HRE-ODD-luc Cells for Surgical Implantation
- 04:36Surgical Implantation of MDA-MB231/5HRE-ODD-luc Cells into the Mouse Brain
- 06:23In vivo Bioluminescence Imaging of Tumor Hypoxia Dynamics in Breast Cancer Brain Metastasis
- 08:23Representative Results In vitro and In vivo Bioluminescence Assays
- 10:35Conclusion
Tags
In Vivo Bioluminescence ImagingTumor Hypoxia DynamicsBreast Cancer Brain MetastasisMouse ModelMalignant ProgressionTherapeutic ResponseIntracranial DevelopmentOrthotopic TumorsBioluminescence Imaging (BLI)Luciferase Gene ExpressionCancer ResearchTumor GrowthTreatment ResponseReporter GeneHypoxia Inducible Factor-1α (HIF-1α)Gene TranscriptionMDA-MB231 CellsHIF-1α Bioluminescence AssayHypoxic ChamberPhoton Flux
