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In-vivo-Biolumineszenz-Bildgebung von Tumorhypoxie Dynamics of Breast Cancer Hirnmetastasen in einem Mausmodell
JoVE Journal
Medicine
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JoVE Journal Medicine
In vivo Bioluminescence Imaging of Tumor Hypoxia Dynamics of Breast Cancer Brain Metastasis in a Mouse Model
DOI:

11:02 min

October 03, 2011

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Chapters

  • 00:05Title
  • 01:46Validation of MDA-MB231/5HRE-ODD-luc Cells as a Tool for Measuring Hypoxia Dynamics
  • 04:03Culture of MDA-MB231/5HRE-ODD-luc Cells for Surgical Implantation
  • 04:36Surgical Implantation of MDA-MB231/5HRE-ODD-luc Cells into the Mouse Brain
  • 06:23In vivo Bioluminescence Imaging of Tumor Hypoxia Dynamics in Breast Cancer Brain Metastasis
  • 08:23Representative Results In vitro and In vivo Bioluminescence Assays
  • 10:35Conclusion

Summary

Automatic Translation

Biolumineszenz-Bildgebung des Hypoxie-induzierbaren Faktors-1α Aktivität wird angewandt, um intrakranielle Tumorhypoxie Entwicklung in einer Brustkrebs Hirnmetastasen Mausmodell zu überwachen.

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