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A Neonatal Rodent Model of Retroorbital Vein Injection
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
A Neonatal Rodent Model of Retroorbital Vein Injection

A Neonatal Rodent Model of Retroorbital Vein Injection

DOI:
10.3791/65386-v

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04:39 min

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February 23, 2024

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, , , , , ,
1Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology, Sahlgrenska Academy,University of Gothenburg, 2Centre of Perinatal Medicine and Health, Institute of Neuroscience and Physiology, Sahlgrenska Academy,University of Gothenburg

Chapters

  • 00:11Introduction
  • 01:47Needle and Solution
  • 02:01Setup
  • 02:23Injection Procedure
  • 03:15Representative Results
  • 04:01Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol aims to demonstrate a reproducible venous administration route that can be used in rats and mice throughout the neonatal period. This procedure is important for preclinical rodent studies that wish to mirror drug administration in neonatal care units primarily using intravenous administration.

Tags

Retroorbital Vein InjectionNeonatal Rodent ModelIntravenous InjectionAnimal ResearchTail Vein InjectionVenous CirculationOrbital Venous AnatomyTrypan BlueIsoflurane AnesthesiaPull Withdrawal Reflex

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