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Journal
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Immunology and Infection
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用于过敏性接触性皮炎评估的小鼠耳模型
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Please note that all translations are automatically generated.
Click here for the English version.
用于过敏性接触性皮炎评估的小鼠耳模型
DOI:
10.3791/65120-v
•
08:02 min
•
March 24, 2023
•
Haifeng Shao
2,3,4
,
Jialin Deng
3,4
,
Yanqing Liu
2,3,4
,
Niuniu Yang
2,3,4
1
Department of Traditional Chinese Medicine, The Affiliated Hospital of Yangzhou University
,
Yangzhou University
,
2
Department of Traditional Chinese and Western Medicine, Medical College
,
Yangzhou University
,
3
The Key Laboratory of Syndrome Differentiation and Treatment of Gastric Cancer of the State Administration of Traditional Chinese Medicine
,
Yangzhou University
,
4
Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases
,
Yangzhou University
Chapters
00:04
Introduction
00:55
Animal Preparation
01:35
Abdominal Sensitization Stimulation
02:46
Ear Sensitization Stimulation
03:38
Recording Mouse Weight and Allergic Contact Dermatitis (ACD) Symptoms
04:16
Measurement of the Auricle Thickness
04:50
Evaluation of the Degree of Inflammatory Swelling
05:59
Results: Evaluating the Severity of Allergic Contact Dermatitis
07:32
Conclusion
Summary
Automatic Translation
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Automatic Translation
在这里,我们描述了通过1-氟-2,4-二硝基苯(DNFB)诱导小鼠耳朵过敏性接触性皮炎的方法以及如何评估过敏性接触性皮炎的严重程度。
Tags
Mouse Ear Model
Allergic Contact Dermatitis
DNFB
Sensitization
Ear Stimulation
Weight Changes
Preclinical Evaluation
Animal Model
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