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Journal
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Immunology and Infection
/
在大鼠模型中通过结扎和脂多糖注射的组合
诱导
牙周炎
JoVE Journal
Immunology and Infection
Author Produced
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JoVE Journal
Immunology and Infection
Induction of Periodontitis
via
a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model
Please note that all translations are automatically generated.
Click here for the English version.
在大鼠模型中通过结扎和脂多糖注射的组合
诱导
牙周炎
DOI:
10.3791/64842-v
•
06:14 min
•
February 17, 2023
•
Marta Munar-Bestard
2
,
Oscar Villa
,
Maria del Mar Ferrà-Cañellas
2,3
,
Joana Maria Ramis
2,4,5
,
Marta Monjo
2,4,5
1
Group of Cell Therapy and Tissue Engineering, Research Institute on Health Sciences (IUNICS)
,
University of the Balearic Islands (UIB)
,
2
Balearic Islands Health Research Institute (IdISBa)
,
3
Preclinical Research Department
,
Labo’Life España
,
4
Departament de Biologia Fonamental i Ciències de la Salut
,
UIB
,
5
ADEMA School of Dentistry
,
UIB
Chapters
00:04
Introduction
00:55
Animal Anesthesia and Procedure Preparation
02:48
Retentive Ligature Technique and Intragingival Pg‐LPS Injection
03:42
Post‐Procedure Follow‐Up
04:47
Results: Analysis of the Alveolar Bone and Maxillary Molars
05:46
Conclusion
Summary
Automatic Translation
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Automatic Translation
在这项研究中,通过保留结扎和重复注射源自
牙龈卟啉单
胞菌的脂多糖的组合,在第上颌磨牙周围超过14天
,提出了
诱导牙周炎的大鼠模型。结扎和LPS注射技术可有效诱发牙周炎,导致牙槽骨质流失和炎症。
Tags
Periodontitis
Rat Model
Ligature
Lipopolysaccharide
Experimental
Inflammatory Response
Alveolar Bone Resorption
Periodontal Disease
Treatment Evaluation
Article
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