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小鼠自发性自身免疫性甲状腺炎模型的产生
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Immunology and Infection
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JoVE Journal Immunology and Infection
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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小鼠自发性自身免疫性甲状腺炎模型的产生

DOI:
10.3791/64609-v

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04:39 min

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March 17, 2023

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, , , ,
1Thyroid and Parathyroid Surgery Center,West China Hospital of Sichuan University, 2The Laboratory of Thyroid and Parathyroid Disease,West China Hospital of Sichuan University, 3State Key Laboratory of Biotherapy and Cancer Center, West China Hospital,Sichuan University and Collaborative Innovation Center

Chapters

  • 00:04Introduction
  • 00:49Thyroid Tissue Sample Preparation
  • 02:06Results: Assessment of Autoantibodies, TSH, and T4 levels
  • 03:41Conclusion

Summary

Automatic Translation

Automatic Translation

桥本甲状腺炎的几种动物模型已经建立，NOD小鼠的自发性自身免疫性甲状腺炎也是如此。H-2h4小鼠是一种简单可靠的HT诱导模型。本文介绍了这种方法并评估了病理过程，以便更好地了解SAT小鼠模型。

Tags

Autoimmune ThyroiditisMouse ModelThyroid GlandIodine IntakePathological ChangesLymphocytic InfiltrationThyroglobulin AntibodyThyroid Peroxidase AntibodyTSHT4

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