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Journal
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Neuroscience
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基于微创技术的小鼠挫伤脊髓损伤模型的建立
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal
Neuroscience
Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
Please note that all translations are automatically generated.
Click here for the English version.
基于微创技术的小鼠挫伤脊髓损伤模型的建立
DOI:
10.3791/64538-v
•
07:17 min
•
September 07, 2022
•
Elham Yilizati-Yilihamu Elzat
,
Xiangchuang Fan
,
Zimeng Yang
,
Zhongze Yuan
,
Yilin Pang
,
Shiqing Feng
2
1
Department of Orthopaedics
,
Qilu Hospital of Shandong University
,
2
Department of Orthopaedics
,
Tianjin Medical University General Hospital
Chapters
00:05
Introduction
01:06
Mechanism of the Spinal Cord Injury Coaxial Platform and Mechanical Tests
02:02
Locating and Laminectomy of the 9
th
Thoracic Vertebra (T9)
04:11
T9 Contusion Injury
05:23
Results: Sagittal Sections on the 1
st
and 56
th
Days After Injury to the Spinal Cord of Mice
06:38
Conclusion
Summary
Automatic Translation
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Automatic Translation
微创技术和简单的实验室设备通过减少对实验动物的手术损伤并允许解剖形态维持来提高脊髓损伤模型的可重复性。该方法是值得的,因为可靠的结果和可重复的程序有助于研究疾病修复的机制。
Tags
Mouse Contusion Spinal Cord Injury
Minimally Invasive Technique
Anatomical Structure
Weight Drop
Spinal Cord Locating
Laminectomy
Paraspinal Muscle Dissection
Microenvironment Analysis
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