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Journal
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Cancer Research
/
斑马鱼幼虫作为评估潜在放射增敏剂或保护剂的模型
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JoVE Journal
Cancer Research
Zebrafish Larvae as a Model to Evaluate Potential Radiosensitizers or Protectors
Please note that all translations are automatically generated.
Click here for the English version.
斑马鱼幼虫作为评估潜在放射增敏剂或保护剂的模型
DOI:
10.3791/64233-v
•
04:53 min
•
August 25, 2022
•
Amlan P. Mohapatra*
1,3
,
Deepti Parida*
1,3
,
Debasish Mohapatra
4
,
Usharani Nayak
3
,
Rajeeb K. Swain
,
Shantibhusan Senapati
1
Tumor microenvironment and animal models lab
,
Institute of Life Sciences
,
2
Vascular Biology lab
,
Institute of Life Sciences
,
3
Regional Centre for Biotechnology
,
4
School of Biotechnology
,
KIIT University
Chapters
00:04
Introduction
00:57
Monitoring Embryos and Selection for Radiation Experiments
01:28
X‐Ray Irradiation
02:38
Data Collection, Imaging, and Analysis
03:17
Results: Effect of Different Doses of X‐Ray Irradiation on 6 hpf Zebrafish Embryos
04:23
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
斑马鱼最近被用作验证潜在辐射改性剂的模型。本方案描述了使用斑马鱼胚胎进行基于辐射的筛选实验的详细步骤以及一些观察方法来评估不同治疗和辐射的效果。
Tags
Zebrafish Larvae
Radiation Screening
Radiosensitizers
Radioprotectors
Radiation-based Experiments
High-throughput Drug Screening
Radiobiology
Radiotherapy
X-ray Irradiation
Embryo Staging
Observational Approaches
Survival
Hatching Efficiency
Developmental Stages
Phenotypic Changes
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