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分子和免疫技术在胃肠道间质瘤基因工程小鼠模型中
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Cancer Research
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JoVE Journal Cancer Research
Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor
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分子和免疫技术在胃肠道间质瘤基因工程小鼠模型中

DOI:
10.3791/63853-v

•

07:21 min

•

May 02, 2022

•

, , , , ,
1Department of Surgery,Hospital of the University of Pennsylvania

Chapters

  • 00:05Introduction
  • 00:42KitV558Δ/+ Mouse Organ Harvest
  • 02:26Single-Cell Suspension of Mesenteric Lymph Node
  • 03:09Single-Cell Suspension of GIST
  • 04:22Single-Cell Suspension of Cecum
  • 06:06Results: Investigation of Therapeutics in an Immunocompetent Mouse Model
  • 06:49Conclusion

Summary

Automatic Translation

Automatic Translation

本手稿的目的是描述 试剂盒V558Δ/+小鼠模型以及成功解剖和处理小鼠标本的技术。

Tags

Genetically Engineered Mouse ModelGastrointestinal Stromal Tumor (GIST)ImmunocompetentMolecular TechniquesImmunologic TechniquesTyrosine Kinase InhibitorsImmunotherapiesCecumMesenteric Lymph NodeSingle-cell SuspensionFlow Cytometry

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