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Cancer Research
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建立胰腺癌斑马鱼患者来源的异种移植物进行化学敏感性测试
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Cancer Research
Establishment of Zebrafish Patient-Derived Xenografts from Pancreatic Cancer for Chemosensitivity Testing
Please note that all translations are automatically generated.
Click here for the English version.
建立胰腺癌斑马鱼患者来源的异种移植物进行化学敏感性测试
DOI:
10.3791/63744-v
•
06:59 min
•
May 12, 2023
•
Alice Usai
,
Gregorio Di Franco
,
Chiara Gabellini
,
Luca Morelli
,
Vittoria Raffa
1
Department of Biology
,
University of Pisa
,
2
General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery
,
University of Pisa
Chapters
00:04
Introduction
00:56
Sample Processing
03:11
Establishment of Zebrafish‐Based Patient‐Derived Xenografts (zPDX)
04:56
Treatment and Imaging
05:40
Results: Establishment of Zebrafish‐Based Patient‐Derived Xenografts (zPDXs) from Primary Human Pancreatic Adenocarcinoma
06:14
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
临床前模型旨在提高癌症生物学知识并预测治疗效果。本文描述了基于斑马鱼的患者来源的带有肿瘤组织碎片的异种移植物(zPDX)的产生。zPDXs用化疗治疗,根据移植组织的细胞凋亡评估其治疗效果。
Tags
Zebrafish
Patient-derived Xenograft
PDX
Pancreatic Cancer
Chemosensitivity Testing
Tumor Microenvironment
Personalized Medicine
Cell Staining
Xenograft Establishment
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