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Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Application of Elastase
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Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Application of Elastase

Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Application of Elastase

DOI:
10.3791/63608-v

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04:49 min

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February 11, 2022

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, , , ,
1Department of Internal Medicine, Frankel Cardiovascular Center,University of Michigan, Ann Arbor

Chapters

  • 00:04Introduction
  • 01:03Surgery Procedure
  • 03:30Results: Standardization of Surgical Method for the Elastase-Induced AAA Model
  • 04:21Conclusion

Summary

Automatic Translation

Automatic Translation

The present protocol describes a standardized surgical method for the elastase-induced AAA model through the direct application of elastase to the adventitia of infrarenal abdominal aorta in mice.

Tags

MouseAbdominal Aortic AneurysmElastasePerivascular ApplicationStandardized ProtocolReproducibilityCarprofenAnesthesiaIncisionAbdominal CavityAortaInferior Vena CavaCotton PadElastase IncubationSaline IrrigationSuture

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