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Journal
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Immunology and Infection
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在盲肠结扎和穿刺诱导的脓毒症小鼠模型中评估可靠的生物标志物
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Immunology and Infection
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JoVE Journal
Immunology and Infection
Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Please note that all translations are automatically generated.
Click here for the English version.
在盲肠结扎和穿刺诱导的脓毒症小鼠模型中评估可靠的生物标志物
DOI:
10.3791/63584-v
•
05:28 min
•
December 09, 2022
•
Li Yaozhen
,
Wu Kemin
,
Ji Xiaoyu
,
Ouyang Yang
,
Tang Hongying
,
Pan Baihong
1
Department of Vascular Surgery, Xiangya Hospital
,
Central South University
Chapters
00:14
Introduction
00:49
Preparation
01:15
Operation
03:53
Treatment
04:52
Representative Results
05:16
Conclusion
Summary
Automatic Translation
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Automatic Translation
该协议介绍了脓毒症小鼠模型中盲肠结扎和穿刺（CLP）的操作细节。CLP是创建脓毒症动物模型的最广泛使用的技术之一。因此，需要标准化的CLP协议才能获得可靠的研究结果。
Tags
Cecal Ligation And Puncture
CLP
Sepsis
Mouse Model
Biomarker
Citrullinated Histone H3
CitH3
NETosis
C57BL/6 Mice
Abdominal Surgery
Anesthesia
Ketoprofen
Euthanasia
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