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1Department of Cardiothoracic and Vascular Surgery,German Heart Center Berlin (DHZB), 2Institute of Physiology,Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 3DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, 4Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health
Chapters
- 00:05Introduction
- 00:42Surgical Preparations and Tracheotomy and Mechanical Ventilation
- 02:24Aortic Debanding
- 04:06Tracheal Extubation and Post-Operative Care
- 05:19Results: Analysis of Aortic Blood Flow, Ventricular Function, and Hemodynamics after Debanding Surgery
- 07:09Conclusion
O presente protocolo descreve um procedimento cirúrgico para remover a faixa ascendente-aórtica em um modelo de rato de hipertensão pulmonar devido a doença cardíaca esquerda. Esta técnica estuda mecanismos endógenos de remodelação reversa na circulação pulmonar e no coração direito, informando estratégias para reverter a hipertensão pulmonar e/ou disfunção ventricular direita.
