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Oprode Array para modulação optogenética simultânea e gravação neural elétrica
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1Department of Electronic and Electrical Engineering,Ewha Womans University, 2Graduate Program in Smart Factory,Ewha Womans University, 3Department of Electrical and Computer Engineering,Seoul National University, 4Graduate School of Engineering Practice,Seoul National University, 5Department of Brain and Cognitive Sciences,Ewha Womans University
Chapters
- 00:04Introduction
- 01:13Preparation of an Optrode Array
- 01:39Presurgical Preparation of Animal and Implantation Surgery
- 03:45Setting Parameters and Conducting Optogenetic Stimulation, Electrophysiological Recording, and Data Analysis
- 04:55Results: Electrophysiological Recording
- 05:40Conclusion
Aqui, apresentamos o método de fabricação de um sistema optrode com fibras ópticas para entrega de luz e uma matriz de eletrodos para gravação neural. Experimentos in vivo com camundongos transgênicos expressando channelrhodopsin-2 mostram a viabilidade do sistema para estimulação optogenética simultânea e gravação eletrofisiológica.
