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机械冲突避免测定测量小鼠疼痛行为
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Neuroscience
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JoVE Journal Neuroscience
Mechanical Conflict-Avoidance Assay to Measure Pain Behavior in Mice
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机械冲突避免测定测量小鼠疼痛行为

DOI:
10.3791/63454-v

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06:57 min

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February 18, 2022

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, , , ,
1Laboratories of Neuroimmunology, Department of Symptom Research, and the MD Anderson Pain Research Consortium,University of Texas MD Anderson Cancer Center, 2Department of Anesthesiology, Perioperative and Pain Medicine,Stanford University School of Medicine

Chapters

  • 00:04Introduction
  • 00:39Mechanical Conflict-Avoidance (MCA) Construction
  • 02:27Mouse MCA Habituation and Testing
  • 04:49Results: MCA Assay Analysis of Inflammatory, Neuropathic, and Fracture/Casting Induced Pain Augmentation Avoidance
  • 06:20Conclusion

Summary

Automatic Translation

Automatic Translation

机械避免冲突测定用作小鼠疼痛敏感性的非反射性读数，可用于更好地理解各种小鼠疼痛模型中的情感动机反应。

Tags

Mechanical Conflict-avoidance AssayPain BehaviorMicePreclinical ResearchTranslational ResearchAcrylic ChamberLED IlluminationProbe ArrayNylon 12 PlasticAcclimationVideo Recording

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