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Journal
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Neuroscience
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恒河猴脑脊液中Aβ和Tau水平重复经颅磁刺激的试点研究
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
A Pilot Study on the Repetitive Transcranial Magnetic Stimulation of Aβ and Tau Levels in Rhesus Monkey Cerebrospinal Fluid
Please note that all translations are automatically generated.
Click here for the English version.
恒河猴脑脊液中Aβ和Tau水平重复经颅磁刺激的试点研究
DOI:
10.3791/63005-v
•
06:22 min
•
September 03, 2021
•
Ling-Yi Liao
2,3
,
Ying-Qian Zhang
,
Benson Wui-Man Lau
,
Qiong Wu
,
Zi-Yan Fan
3
,
Qiang Gao
3
,
Zhi-Hui Zhong
7
1
Department of Rehabilitation Medicine, West China Hospital
,
Sichuan University
,
2
Department of Rehabilitation Medicine, Daping Hospital
,
Army Medical University
,
3
Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital
,
Sichuan University
,
4
Department of physiology
,
Southwest Medical University
,
5
Department of Rehabilitation Sciences
,
The Hong Kong Polytechnic University
,
6
Laboratory of Nonhuman Primate Disease Modeling Research, State Key Laboratory of Biotherapy, West China Hospital
,
Sichuan University
,
7
Sichuan Kangcheng Biotech Co., Inc.
Chapters
00:04
Introduction
00:50
Serial Cisterna Magna Cerebrospinal Fluid (CSF) Sampling Method
02:34
Monkey Chair Adaptive Training
03:07
rTMS Adaptive Training/Sham Stimulation
03:39
Treatment Protocol
04:07
CSF Biomarkers, CSF Collection, and Index Detection Method
04:40
Results: Effect of rTMS Stimulation with Different Frequencies on Aβ and Tau Metabolism
05:57
Conclusion
Summary
Automatic Translation
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Automatic Translation
在这里,我们描述了一项试点研究的程序,以探索不同频率(1 Hz / 20 Hz / 40 Hz)的重复经颅磁刺激对恒河猴脑脊液中Aβ和tau代谢的影响。
Tags
Keyword Extraction:Repetitive Transcranial Magnetic Stimulation
Alpha-beta
Tau
Rhesus Monkey
Cerebrospinal Fluid
Cisterna Magna
CSF Sampling
Anesthesia
Spinal Needle
Epidural Catheter
Subarachnoid Space
Sampling Port
Biomarker Analysis
RTMS Intervention
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