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A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers
JoVE Journal
Medicine
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JoVE Journal Medicine
A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers
DOI:

11:58 min

August 21, 2021

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Chapters

  • 00:13Introduction
  • 00:39Preparation of Animals and Operative Setup
  • 01:07Median Laparotomy
  • 01:36Mobilizing the Stomach
  • 02:42Identify and Divide the Jejunum
  • 03:52Stapling the Stomach
  • 04:49Gastrojejunostomy
  • 08:24Jejunojejunostomy
  • 09:56Reposition the Bowel and Stomach
  • 10:20Abdominal Closure
  • 10:47Results
  • 11:28Conclusion

Summary

Automatic Translation

Roux-en-Y gastric bypass (RYGB) is performed to treat obesity and diabetes. However, the mechanisms underlying RYGB's efficacy are not fully understood, and studies are limited by technical difficulty leading to high mortality in animal models. This article provides instructions on how to perform RYGB in rats with high success rates.

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