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Journal
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Immunology and Infection
/
穆林·德克斯特兰硫酸钠诱导结肠炎模型中肠道炎症的系统评分分析
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
Please note that all translations are automatically generated.
Click here for the English version.
穆林·德克斯特兰硫酸钠诱导结肠炎模型中肠道炎症的系统评分分析
DOI:
10.3791/62135-v
•
09:11 min
•
February 14, 2021
•
Vicky Garcia-Hernandez
,
Philipp-Alexander Neumann
,
Stefan Koch
4
,
Renae Lyons
,
Asma Nusrat
,
Charles A. Parkos
1
Department of Pathology
,
University of Michigan
,
2
Department of Surgery, Klinikum Rechts der Isar
,
Technische Universität München
,
3
Wallenberg Centre for Molecular Medicine
,
Linköping University
,
4
Department of Biomedical and Clinical Sciences (BKV)
,
Linköping University
Chapters
00:04
Introduction
00:50
Tissue Harvest
02:24
Preparation of Swiss Rolls
03:57
Digital Scanning and Analysis
06:33
Results: Histological Colitis Score and Percentage of Injury and Ulceration Correlates with Body Weight and Stool Index During DSS Experimental Colitis
08:30
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
使用免费计算机辅助系统系统地对肠道炎症进行评分,是定量比较以溃疡和炎症变化为特征的结肠炎模型组织病理变化的有力工具。病理结肠炎评分评估加强临床观察,便于数据解释。
Tags
Keyword Extraction:Systematic Scoring Analysis
Intestinal Inflammation
Murine Dextran Sodium Sulfate-induced Colitis Model
Mucosal Injury
Histological Interpretation
Quantitative Analysis
Intestines
Mice
Colitis
Euthanized Mouse
Dissecting Pad
Abdominal Skin
Peritoneum
Large Intestine
Pelvic Bone
Colon
PBS
Western Blot
PCR
Immunofluorescence Microscopy
Neutral Buffered Formalin Solution
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