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植入遥测心电图和血压递质组合以确定意识小鼠的自发压力反射敏感性
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
Please note that all translations are automatically generated.
Click here for the English version.
植入遥测心电图和血压递质组合以确定意识小鼠的自发压力反射敏感性
DOI:
10.3791/62101-v
•
09:56 min
•
February 14, 2021
•
René D. Rötzer
,
Verena F. Brox
,
Konstantin Hennis
,
Stefan B. Thalhammer
,
Martin Biel
2
,
Christian Wahl-Schott
,
Stefanie Fenske
2
1
Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy
,
Ludwig-Maximilians-Universität München
,
2
German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance
,
3
Hannover Medical School
,
Institute for Neurophysiology
Chapters
00:05
Introduction
01:34
Dissection of the Left Common Carotid
04:09
Cannulation of the Left Common Carotid Artery
05:11
Placement of the Telemetry Device Body and ECG Leads
07:29
Results: Analysis of BRS Using the Sequence Method on Simultaneous Telemetric ECG and BP Recordings
08:58
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
压力反射是自主神经系统响应血压变化的心率调节机制。我们描述了一种植入遥测发射器的手术技术,用于连续和同时测量小鼠的心电图和血压。这可以确定自发性压力反射敏感性,这是心血管疾病的重要预后标志物。
Tags
Telemetry
ECG
Blood Pressure
Baroreflex Sensitivity
Conscious Mice
Cardiovascular Disease
Microsurgery
Carotid Artery
Anesthesia
Depilatory Cream
Skin Incision
Blunt Dissection
Parotid Gland
Submandibular Gland
Trachea
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