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Fertility Preservation in Patients with Severe Ovarian Dysfunction
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JoVE Journal Medicine
Fertility Preservation in Patients with Severe Ovarian Dysfunction

Fertility Preservation in Patients with Severe Ovarian Dysfunction

DOI:
10.3791/62098-v

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12:03 min

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March 25, 2021

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1Advanced Reproduction Medicine Research Center, Department of Obstetrics and Gynecology,International University of Health and Welfare School of Medicine

Chapters

  • 00:00Introduction
  • 02:35Background
  • 04:41Drug-free IVA Procedure
  • 05:35Ovarian Cortex Fragmentation
  • 06:37Remove Residual Medulla Tissue
  • 07:43Preparation of Ovarian Cortical Cubes
  • 09:34Loading Ovarian Cortical Fragments
  • 10:10Loading Cortical Cubes
  • 10:50Results
  • 11:22Conclusion

Summary

Automatic Translation

Automatic Translation

We present details of laboratory procedures for drug-free in vitro activation (IVA) of ovarian follicles for patients with severe ovarian dysfunction. This method could increase the number of retrievable oocytes per ovarian hyperstimulation and benefit fertility preservation for those patients.

Tags

Fertility PreservationOvarian DysfunctionOvarian ReservePoor Ovarian ResponseOocyte CryopreservationIn Vitro Activation (IVA)Hippo SignalingAkt SignalingDrug-free IVASecondary Follicle GrowthBologna CriteriaLaparoscopyPoor Ovarian Responder (POR)

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