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通过胆管 TNBS 输液治疗慢性胰腺炎的鼠标模型

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JoVE Journal Medicine

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

Please note that all translations are automatically generated. Click here for the English version.

通过胆管 TNBS 输液治疗慢性胰腺炎的鼠标模型

DOI:

10.3791/62080-v

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06:44 min

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February 28, 2021

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Wenyu Gou*¹, Lindsay Swaby*¹, A. Marissa Wolfe, William P. Lancaster², Katherine A. Morgan, Hongjun Wang²

¹Department of Surgery,Medical University of South Carolina, ²Ralph H. Johnson Veterans Affairs Medical Center

Chapters

00:04Introduction
00:52Mouse Monitoring and Surgery
04:03Results: Representative Effect of Bile Duct TNBS Infusion in a Mouse Chronic Pancreatitis Model
05:48Conclusion

Summary

Automatic Translation

慢性胰腺炎（CP）是一种以胰腺炎症和纤维化为特征的疾病，通常与难以克服的腹痛有关。本文侧重于改进技术，通过胆管输液产生CP的小鼠模型与2，4，6-三硝基苯硫酸（TNBS）。

Tags

Mouse Model Chronic Pancreatitis Bile Duct TNBS Infusion Neuropathic Pain Von Frey Monofilaments TNBS Solution Pancreatic Duct Abdominal Pain Fibrosis Inflammation

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