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通过压力-体积环路分析确定心脏对β肾上腺素能刺激的反应
JoVE Journal
Medicine
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JoVE Journal Medicine
Cardiac Response to β-Adrenergic Stimulation Determined by Pressure-Volume Loop Analysis
DOI:

08:05 min

May 19, 2021

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Chapters

  • 00:04Introduction
  • 00:42Femoral Cannulation
  • 01:51Thoracotomy
  • 02:58Pressure Volume Loop (PVL) Measurement
  • 04:15PVL Parallel-Conductance Calibration
  • 04:54PVL Conductance-to-Volume Calibration
  • 05:32Results: Representative PVL Analysis
  • 07:11Conclusion

Summary

Automatic Translation

在这里,我们描述了在增加静脉输注的异丙肾上腺素剂量下的心脏压力 - 体积环路分析,以确定小鼠的内在心脏功能和β肾上腺素能储备。我们使用改进的开胸方法进行压力 - 体积回路测量,其中我们包括具有正呼气末压的通气。

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