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A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
JoVE Journal
Medicine
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JoVE Journal Medicine
A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
DOI:

04:21 min

August 04, 2021

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Chapters

  • 00:04Introduction
  • 01:08Intratracheal Instillation (ITI) and Characterization Post Administration
  • 03:07Results: Validation of Intratracheal Instillation Technique
  • 03:50Conclusion

Summary

Automatic Translation

This technique of instilling drugs directly into the trachea of neonatal rodents is important in studying the impact of locally administered drugs or biologicals on neonatal lung diseases. Additionally, this method can also be used for inducing lung injury in animal models.

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