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在穆林模型中缺血再灌注损伤后干细胞的心肌内传递延迟
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JoVE Journal
Medicine
Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model
Please note that all translations are automatically generated.
Click here for the English version.
在穆林模型中缺血再灌注损伤后干细胞的心肌内传递延迟
DOI:
10.3791/61546-v
•
07:50 min
•
September 03, 2020
•
Michaela Olthoff
,
Federico Franchi
,
Karen M. Peterson
,
Ramasamy Paulmurugan
,
Martin Rodriguez-Porcel
1
Department of Cardiovascular Medicine
,
Mayo Clinic
,
2
Department of Radiology and Molecular Imaging Program at Stanford (MIPS)
,
Stanford University School of Medicine
Chapters
00:04
Introduction
00:54
Preparation and Intubation
02:10
Ischemia Reperfusion Injury
04:15
Mouse Mesenchymal Stem Cell Delivery
06:07
Results: Heart Function after Ischemic Injury
07:05
Conclusion
Summary
Automatic Translation
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干细胞作为心肌损伤患者的潜在治疗方法不断被研究,然而,干细胞在损伤组织中生存能力的降低和保留会影响其长期疗效。在这份手稿中,我们描述了一种替代干细胞传递方法,该模型采用缺血再灌注损伤的穆林模型。
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Stem Cell Therapy
Ischemia-reperfusion Injury
Delayed Cell Delivery
Surgical Procedure
Murine Model
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