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1Department of Neurology, Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan 430000, China, 2Key Laboratory of Neurological Diseases of Chinese Ministry of Education, The School of Basic Medicine, Tongji Medical College,Huazhong University of Science and Technology, Wuhan 430000,China, 3Department of Pharmacology, School of Basic Medical Science; State Key Laboratory of Medical Neurobiology,Institutes of Brain Science and Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China
Chapters
- 00:04Introduction
- 01:06Mouse Screening Preparation
- 01:58Chronic Sleep Fragmentation (CSF) Modeling
- 03:04Morris Water Maze (MWM) Test
- 04:00Results: Representative Effects of CSF Modeling on Young Wild-Type Mouse Cognitive Abilities and Anxiety-Like Behaviors
- 05:34Conclusion
يُعرض هنا بروتوكول لنموذج تفتيت النوم المزمن (CSF) الذي حققه دوار مداري يتم التحكم فيه كهربائيًا ، والذي يمكن أن يحفز العجز المعرفي المؤكد والسلوك الشبيه بالقلق في الفئران البرية الشابة. يمكن تطبيق هذا النموذج لاستكشاف التسبب في اضطرابات النوم المزمنة والاضطرابات ذات الصلة.
