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前维沃·兰根多夫注入心脏的心电生理学研究
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
Please note that all translations are automatically generated.
Click here for the English version.
前维沃·兰根多夫注入心脏的心电生理学研究
DOI:
10.3791/60472-v
•
09:52 min
•
November 07, 2019
•
Luther M. Swift
2
,
Rafael Jaimes III
2
,
Damon McCullough
2
,
Morgan Burke
2
,
Marissa Reilly
2
,
Takuya Maeda
2,3
,
Hanyu Zhang
,
Nobuyuki Ishibashi
2,3
,
Jack M. Rogers
,
Nikki Gillum Posnack
2,5
1
Sheikh Zayed Institute for Pediatric Surgical Innovation
,
Children’s National Hospital
,
2
Children’s National Heart Institute
,
Children’s National Hospital
,
3
Center for Neuroscience Research
,
Children’s National Hospital
,
4
Department of Biomedical Engineering, School of Engineering
,
University of Alabama at Birmingham
,
5
Department of Pediatrics, Department of Pharmacology & Physiology, School of Medicine and Health Sciences
,
George Washington University
Chapters
00:05
Title
01:02
Heart Excision and Langendorff Perfusion
02:42
Electrophysiology Study
05:17
Transmembrane Voltage and Intracellular Calcium Optical Mapping
06:55
Cleanup
07:20
Results: Representative Optical Data from Langendorff-Perfused Model Hearts
08:59
Conclusion
Summary
Automatic Translation
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Automatic Translation
本研究的目的是建立一种使用转化动物模型调查心脏动力学的方法。所述的实验方法将双发射心电图与电生理学研究相结合,以评估孤立、完整的猪心脏模型中的电活动。
Tags
Optocardiography
Electrophysiology
Langendorff-perfused Hearts
Cardiovascular Malfunction
Disease Modeling
Pharmacology
Toxicology
Glass Sizers
Cardiac Electrophysiology
Imaging
Perfusion System
Cardioplegia
Krebs-Henseleit Medium
Defibrillation
Cardioversion
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