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重建显微外科缺血再灌注损伤研究的临床前大鼠模型
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
Please note that all translations are automatically generated.
Click here for the English version.
重建显微外科缺血再灌注损伤研究的临床前大鼠模型
DOI:
10.3791/60292-v
•
08:05 min
•
November 08, 2019
•
Alberto Ballestín
,
Javier G. Casado
,
Elena Abellán
,
Francisco Javier Vela
,
José Luis Campos
,
Guadalupe Martínez-Chacón
,
Jorge Bote
,
Rebeca Blázquez
,
Francisco Miguel Sánchez-Margallo
2,3
1
Department of Microsurgery
,
Jesús Usón Minimally Invasive Surgery Centre
,
2
Stem Cell Therapy Unit
,
Jesús Usón Minimally Invasive Surgery Centre
,
3
Animal Modelling Unit
,
Jesús Usón Minimally Invasive Surgery Centre
Chapters
00:04
Title
01:26
Free Skin Flap Model Surgery
03:00
Intraoperative Assessment
05:18
Postoperative Assessment and Tissue Sampling
06:00
Results: Ischemia-Reperfusion Injury in Reconstructive Microsurgery
07:03
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
本文描述了一个临床前动物模型,用于研究重建显微外科中缺血再灌注损伤的病理生理学。这种基于大鼠表面的胆皮外胃血管的自由皮瓣模型也可以允许评估不同的疗法和化合物,以抵消缺血-再灌注损伤相关的损伤。
Tags
Pre-clinical Rat Model
Ischemia-reperfusion Injury
Reconstructive Microsurgery
Flap Failure
Superficial Caudal Epigastric Vessels
Ischemia
Reperfusion
Microsurgical Reconstruction
Innate Immunity
Vascular Pedicle
Microcirculatory Perfusion
Microvascular Anastomosis
Transit-time Ultrasound Flowmetry
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