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Immunology and Infection
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单方支气管内酸灌输自我限制急性肺损伤模型
JoVE Journal
Immunology and Infection
This content is Free Access.
JoVE Journal
Immunology and Infection
A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
Please note that all translations are automatically generated.
Click here for the English version.
单方支气管内酸灌输自我限制急性肺损伤模型
DOI:
10.3791/60024-v
•
00:07 min
•
August 30, 2019
•
Alexander H. Tavares
,
Jennifer K. Colby
,
Bruce D. Levy
,
Raja-Elie Edward Abdulnour
1
Pulmonary and Critical Care Medicine, Department of Internal Medicine
,
Brigham and Women’s Hospital, Harvard Medical School
Chapters
00:04
Title
00:53
Hydrochloric Acid (HCL) Preparation
01:39
Surgical Preparation
03:46
Selective Intra-Bronchial HCL Instillation
05:11
Results
06:38
Conclusion
Summary
Automatic Translation
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Automatic Translation
选择性支气管内酸在小鼠左肺中灌输会导致单侧和自我有限的急性肺损伤,从而模拟胃酸吸入引起的人类急性呼吸窘迫综合征(ARDS)。
Tags
Acute Lung Injury
Intra-bronchial Instillation
Nonlethal Model
Inflammatory Response
Hydrochloric Acid
Anesthetized Mouse
Trachea
Surgical Procedure
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