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小型动物正电子发射断层扫描/计算机断层扫描中的连续血液采样支持动脉输入函数的测量
JoVE Journal
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JoVE Journal
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Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
Please note that all translations are automatically generated.
Click here for the English version.
小型动物正电子发射断层扫描/计算机断层扫描中的连续血液采样支持动脉输入函数的测量
DOI:
10.3791/59701-v
•
10:21 min
•
August 08, 2019
•
Teresa Mann
,
Jens Kurth
,
Anne Möller
,
Joanna Förster
,
Brigitte Vollmar
,
Bernd J. Krause
,
Andreas Wree
,
Jan Stenzel*
3
,
Tobias Lindner*
3
1
Institute of Anatomy
,
Rostock University Medical Center
,
2
Department of Nuclear Medicine
,
Rostock University Medical Center
,
3
Core Facility Multimodal Small Animal Imaging
,
Rostock University Medical Center
,
4
Rudolf-Zenker-Institute for Experimental Surgery
,
Rostock University Medical Center
Chapters
00:04
Title
01:05
Animal Catheterization
03:31
Image Acquisition and Reconstruction
06:41
Manual and Online Blood Sampling
08:31
Results: Representative Continuous and Manual Blood Sampling Results
09:47
Conclusion
Summary
Automatic Translation
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Automatic Translation
这里描述了在大鼠PET/CT成像期间连续血液采样的协议,用于测量动脉输入功能(AIF)。演示了导管、系统的校准和设置以及血液放射性的数据分析。生成的数据为后续的生物动力学建模提供输入参数。
Tags
Continuous Blood Sampling
Small Animal
PET/CT
Arterial Input Function
Extracorporeal Arteriovenous Shunt
Biokinetic Modeling
Cross-calibration
Femoral Vein
Femoral Artery
Catheter Placement
Microsurgery
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