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Behavior
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压力增强恐惧学习--创伤后应激障碍的健壮啮齿动物模型
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Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder
Please note that all translations are automatically generated.
Click here for the English version.
压力增强恐惧学习--创伤后应激障碍的健壮啮齿动物模型
DOI:
10.3791/58306-v
•
05:49 min
•
October 13, 2018
•
Abha K. Rajbhandari
2
,
Sarah T. Gonzalez
2
,
Michael S. Fanselow
2,3
1
Department of Psychology
,
University of California, Los Angeles
,
2
Staglin Center for Brain and Behavioral Health
,
University of California, Los Angeles
,
3
Department of Psychiatry and Biobehavioral Sciences
,
University of California, Los Angeles
Chapters
00:04
Title
00:33
Experimental Setup
01:48
SEFL Procedure
04:41
Results: Trauma Animals Show High Levels of Freezing and Lower Shock Reactivity Compared to Controls
05:26
Conclusion
Summary
Automatic Translation
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在这里, 我们描述了进行压力增强恐惧学习 (大我) 实验所需的详细方法, 这是在大鼠和小鼠创伤后应激障碍的临床前模型。该模型利用巴甫洛夫恐惧调理和冻结的各个方面作为对啮齿动物增强恐惧的指标。
Tags
Stress-enhanced Fear Learning
PTSD Model
Rodent Model
Fear Conditioning
Context A
Context B
Foot Shock
Shock Generator
Scrambler
Grid Floor
Plexiglass Insert
Trauma Conditioning
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