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颈动脉介入移植中颈静脉持久性转基因表达的家兔模型
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Medicine
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JoVE Journal
Medicine
A Rabbit Model of Durable Transgene Expression in Jugular Vein to Common Carotid Artery Interposition Grafts
Please note that all translations are automatically generated.
Click here for the English version.
颈动脉介入移植中颈静脉持久性转基因表达的家兔模型
DOI:
10.3791/57231-v
•
13:58 min
•
September 10, 2018
•
Lianxiang Bi*
1
,
Bradley K. Wacker*
1
,
David A. Dichek
1
Department of Medicine
,
University of Washington School of Medicine
Chapters
00:04
Title
00:37
Vein Graft Surgery
06:57
Gene Transfer Surgery after Graft Placement
11:09
Vein Graft Harvest Surgery
12:05
Results: High-level β-galactosidase Expression in Jugular Vein to Common Carotid Artery Interposition Grafts
13:09
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
该方法描述了介入静脉移植在家兔中的位置、移植物的转导以及持久性转基因表达的实现。这允许调查转基因及其蛋白产品在接枝静脉中的生理和病理作用, 以及对静脉移植病基因治疗的检测。
Tags
Rabbit Model
Transgene Expression
Vein Graft
Common Carotid Artery
Graft Failure
Vein Graft Endothelium
Surgical Protocol
Dissection
Ligation
Arteriotomy
Vein Grafting
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