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Behavior
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全身麻醉下小鼠幸福度的系统评价
JoVE Journal
Behavior
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JoVE Journal
Behavior
Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia
Please note that all translations are automatically generated.
Click here for the English version.
全身麻醉下小鼠幸福度的系统评价
DOI:
10.3791/57046-v
•
06:50 min
•
March 20, 2018
•
Katharina Hohlbaum
2
,
Bettina Bert
3
,
Silke Dietze
,
Rupert Palme
,
Heidrun Fink
,
Christa Thöne-Reineke
1
Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine
,
Freie Universität Berlin
,
2
Institute of Pharmacology and Toxicology, Department of Veterinary Medicine
,
Freie Universität Berlin
,
3
German Federal Institute for Risk Assessment (BfR)
,
4
Unit of Physiology, Pathophysiology and Experimental Endocrinology, Department of Biomedical Sciences
,
University of Veterinary Medicine
Chapters
00:05
Title
01:09
Mouse Grimace Scale and Burrowing Behavior
02:36
Nest Building Behavior
03:59
Free Exploratory Paradigm
04:33
Results: Assessment of Mice after General Anesthesia
05:45
Conclusion
Summary
Automatic Translation
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Automatic Translation
我们制定了一个协议, 以评估小鼠的福祉在程序中使用全麻。分析了一系列的行为参数, 说明了幸福水平和糖皮质激素代谢产物。该议定书可作为一般援助, 以科学的、以动物为中心的方式估计严重程度。
Tags
Mouse Welfare
Well-being Assessment
General Anesthesia
EU Directive 2010/63
Mouse Grimace Scale
Burrowing Behavior
Home Cage Activity
Food Intake
Nest Building
Fecal Corticosterone Metabolites
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