Journal
/
Neuroscience
/
戊四氮诱导点燃小鼠模型
JoVE Journal
Neuroscience
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Neuroscience
Pentylenetetrazole-Induced Kindling Mouse Model
Please note that all translations are automatically generated. Click here for the English version.

戊四氮诱导点燃小鼠模型

DOI:
10.3791/56573-v

•

07:06 min

•

June 12, 2018

•

,
1Synaptic Plasticity Project,Tokyo Metropolitan Institute of Medical Science

Chapters

  • 00:04Title
  • 00:38Injection of PTZ
  • 01:20Three Chamber Test
  • 04:18Contextual Fear Discrimination
  • 05:29Results: Repetitive Injection of PTZ Induces an Increase in Seizure Severity
  • 06:26Conclusion

Summary

Automatic Translation

Automatic Translation

本协议描述了一种戊四氮化学点燃方法, 并提供了一种小鼠癫痫模型。该协议还可用于调查小鼠癫痫发作后癫痫诱导和发病机制的脆弱性。

Tags

Pentylenetetrazole-Induced KindlingMouse ModelEpilepsySeizureHistological ChangesNeuropsychiatric DisordersPTZSodium ChlorideIntraperitoneal Injection129 SV MiceThree-Chamber ApparatusHabituationSocial InteractionBehavioral Parameters

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

多鼠神经解剖学磁共振成像

在阿尔茨海默氏症小鼠模型神经炎斑检测

在小鼠模型中静脉自我管理的方法

胰蛋白酶精华协议分析视网膜血管小鼠模型

角膜微囊含量：血管生成在小鼠眼模型

在多发性硬化症的小鼠模型测量进行性神经功能残疾

小鼠新生儿缺氧缺血性脑损伤模型的神经行为评估

在体内小鼠激光诱导脉络膜新生血管模型的多模态成像与分析

小鼠后脑作为研究胚胎神经再生的模型

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy

Read Article