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Journal
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Immunology and Infection
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流感血凝素特异抗体诱导的 Fc 介导效应函数的一种评估方法
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies
Please note that all translations are automatically generated.
Click here for the English version.
流感血凝素特异抗体诱导的 Fc 介导效应函数的一种评估方法
DOI:
10.3791/56256-v
•
04:47 min
•
February 23, 2018
•
Mark J. Bailey
2
,
Felix Broecker
,
Paul E. Leon
2
,
Gene S. Tan
1
Department of Microbiology
,
Icahn School of Medicine at Mount Sinai
,
2
Graduate School of Biomedical Sciences
,
Icahn School of Medicine at Mount Sinai
,
3
Department of Infectious Disease
,
J. Craig Venter Institute
Chapters
00:05
Title
00:42
Influenza Virus Hemagglutinin Expression
02:18
Antibody-dependent Cell-mediated Cytotoxicity (ADCC) Analysis
04:01
Results: Representative ADCC Analysis
04:24
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
我们描述了一种方法来衡量 Fc 介导的效应函数的活化作用的抗体, 针对流感病毒血凝素。这种检测也可以适应评估单克隆抗体或多克隆血清靶向其他病毒表面糖蛋白, 以诱导 Fc 介导的免疫能力。
Tags
Fc-mediated Effector Functions
Influenza Hemagglutinin
Antibody
ADCC
Cell-mediated Cytotoxicity
Transfection
Infection
A549 Cells
293 Cells
Virus
Immunology
Vaccinology
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