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Geração de um modelo de doença pulmonar obstrutiva crônica em ratos pela exposição repetida de ozônio
JoVE Journal
Medicine
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JoVE Journal Medicine
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
DOI:

08:17 min

August 25, 2017

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Chapters

  • 00:05Title
  • 00:52Ozone Air Exposure and Treadmill Test
  • 02:17Pulmonary Function Measurements
  • 03:05Broncheoalveolar Lavage Fluid (BALF) Collection
  • 04:25Cardiac Blood Sampling and Lung Morphometric Analysis
  • 06:06Results: Representative Chronic Obstructive Pulmonary Disease Mouse Model
  • 07:29Conclusion

Summary

Automatic Translation

Este estudo descreve a geração bem sucedida de um novo modelo animal de doença pulmonar obstrutiva crônica (DPOC), repetidamente expondo ratos a concentrações elevadas de ozono.

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