JoVE
JoVE
Faculty Resource Center
Research
Behavior
Biochemistry
Biology
Bioengineering
Cancer Research
Chemistry
Developmental Biology
Engineering
Environment
Genetics
Immunology and Infection
Medicine
Neuroscience
JoVE Journal
JoVE Encyclopedia of Experiments
JoVE Chrome Extension
Education
Biology
Chemistry
Clinical
Engineering
Environmental Sciences
Pharmacology
Physics
Psychology
Statistics
JoVE Core
JoVE Science Education
JoVE Lab Manual
JoVE Quiz
JoVE Business
Videos Mapped to your Course
Authors
Librarians
High Schools
About
Sign-In
Sign In
Contact Us
Research
JoVE Journal
JoVE Encyclopedia of Experiments
Education
JoVE Core
JoVE Science Education
JoVE Lab Manual
High Schools
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
Close
Research
Behavior
Biochemistry
Bioengineering
Biology
Cancer Research
Chemistry
Developmental Biology
Engineering
Environment
Genetics
Immunology and Infection
Medicine
Neuroscience
Products
JoVE Journal
JoVE Encyclopedia of Experiments
Education
Biology
Chemistry
Clinical
Engineering
Environmental Sciences
Pharmacology
Physics
Psychology
Statistics
Products
JoVE Core
JoVE Science Education
JoVE Lab Manual
JoVE Quiz
JoVE Business
Videos Mapped to Your Course
Teacher Resources
Get in Touch
Instant Trial
Log In
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
Journal
/
Neuroscience
/
实验模型研究酸性后处理对脑缺血的神经保护作用
JoVE Journal
Neuroscience
A subscription to JoVE is required to view this content.
Sign in or start your free trial.
JoVE Journal
Neuroscience
Experimental Models to Study the Neuroprotection of Acidic Postconditioning Against Cerebral Ischemia
Please note that all translations are automatically generated.
Click here for the English version.
实验模型研究酸性后处理对脑缺血的神经保护作用
DOI:
10.3791/55931-v
•
10:13 min
•
July 31, 2017
•
Yanrong Zheng*
1
,
Zhe Shen*
1
,
Xiaoli Wu
,
Lei Jiang
,
Weiwei Hu
,
Zhong Chen
,
Xiangnan Zhang
1
Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Department of Pharmacology, Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology
,
Zhejiang University
Chapters
00:05
Title
00:57
Cortical Slice Preparation
02:43
Oxygen-glucose Deprivation and Acidic Postconditioning
04:03
Determination of Slice Viability
05:04
Middle Cerebral Artery Occlusion
07:22
Reperfusion and Acidic Postconditioning
08:16
Results: Acidic Preconditioning Protects Against Reperfusion Injury
09:32
Conclusion
Summary
Automatic Translation
English (Original)
العربية (Arabic)
中文 (Chinese)
Nederlands (Dutch)
français (French)
Deutsch (German)
עברית (Hebrew)
italiano (Italian)
日本語 (Japanese)
한국어 (Korean)
português (Portuguese)
русский (Russian)
español (Spanish)
Türkçe (Turkish)
Automatic Translation
酸性后处理可防止脑缺血。在这里我们提出两个模型来执行APC。分别通过
体外
氧葡萄糖剥夺后将皮质硬膜下切片转移到酸性缓冲液中,并
在体内
大脑中动脉闭塞后吸入20%CO
2
。
Tags
Neuroprotection
Acidic Postconditioning
Cerebral Ischemia
Cortico Striatal Slice Model
Middle Cerebral Artery Occlusion Model
Ischemic Brain Injury
Stroke Therapy
Acidosis Postconditioning
Brain Slice Preparation
Glucose-free ACSF
Acidic ACSF
Synaptic Function Recovery
Article
Embed
ADD TO PLAYLIST
Usage Statistics
Related Videos
研究脑机接口的闭环性能的实验平台
脑血氧测量基于磷光氧依赖淬火
焦距脑缺血模型大鼠大脑中动脉的血管内缝合闭塞
视网膜色素上皮的生理与病理生理学研究的实验模型
儿童使用功能经颅多普勒超声评估大脑偏侧(fTCD)
冷预处理神经保护作用的研究策略
小脑颗粒神经元的遗传操作<em>体外</em>和<em>在体内</em>为研究神经元形态和迁移
在脑血管内皮细胞生物能量功能的评价
脑缺血中风发作时间估计的磁共振成像协议
器官海马切片培养模型研究肿瘤细胞的神经保护和侵袭性
Read Article