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Comportamento invasiva de células de cancro da mama humano em Embryonic Zebrafish
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Invasive Behavior of Human Breast Cancer Cells in Embryonic Zebrafish
DOI:

09:22 min

April 25, 2017

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Chapters

  • 00:05Title
  • 01:28Preparation of Fluorescent Cells
  • 02:42Preparation of Zebrafish Embryos
  • 03:20Xenotransplantation into the Perivitelline Space
  • 05:07Xenotransplantation into the Duct of Cuvier
  • 05:47Invasion and Metastasis Assessment
  • 06:32Results: Xenotransplanted MDA-MB-231, MCF-10A, and MCF-10A-Ras Cells Reveal Distinct Invasiveness Patterns
  • 08:17Conclusion

Summary

Automatic Translation

Aqui, descrevemos modelos peixe-zebra xenotransplante usando dois locais de injecção diferentes, ou seja, espaço perivitelínico e duto de Cuvier, para investigar o comportamento invasivo e avaliar a intravasation e extravasamento potencial das células de câncer de mama humanos, respectivamente.

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