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Cancer Research
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临床前小鼠模型的外科手术和方法<em> De Novo</em>乳腺癌转移
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Cancer Research
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Cancer Research
Surgical Procedures and Methodology for a Preclinical Murine Model of
De Novo
Mammary Cancer Metastasis
Please note that all translations are automatically generated.
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临床前小鼠模型的外科手术和方法<em> De Novo</em>乳腺癌转移
DOI:
10.3791/54852-v
•
08:41 min
•
July 29, 2017
•
Charles E. Gast
,
Aubie K. Shaw
2
,
Melissa H. Wong
3
,
Lisa M. Coussens
3
1
Cell, Developmental & Cancer Biology
,
Oregon Health & Science University
,
2
University of Minnesota
,
3
Knight Cancer Institute
,
Oregon Health & Science University
Chapters
00:00
Title
00:30
Introduction
01:20
Sterilization of Surgical Site
02:06
Primary Tumor Exposure
03:15
Removal of Primary Tumor
06:06
Wound Closure
07:35
Representative Results
07:55
Conclusion
Summary
Automatic Translation
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Automatic Translation
评估靶向乳腺癌转移的辅助治疗的临床前模型缺乏。为了解决这个问题,我们开发了
从头
肺乳腺癌转移,其特征在于,在辅助设定(后手术切除原发肿瘤的)给药的治疗可以为疗效影响先前接种的肺转移进行评估的鼠模型。
Tags
Murine Model
Mammary Cancer
Metastasis
Preclinical
Surgical Resection
MMTV-PyMT
Orthotopic Injection
Primary Tumor
Lung Metastasis
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