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小动物模型尿路感染的实验研究: 男性和女性的经尿道插管
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Immunology and Infection
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JoVE Journal Immunology and Infection
Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
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小动物模型尿路感染的实验研究: 男性和女性的经尿道插管

DOI:
10.3791/54432-v

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10:23 min

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December 01, 2017

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, ,
1Unité d’Immunobiologie des Cellules Dendritiques, Department of Immunology,Institut Pasteur, INSERM U818, 2Genentech

Chapters

  • 00:05Title
  • 00:47Preparation of Catheters and Uropathogenic E. coli for Infection
  • 02:08Transurethral Instillation of Female Mice
  • 03:43Transurethral Instillation of Male Mice
  • 04:56Determination of CFU in Infected Organs
  • 06:09Flow Cytometric Analysis of Bladder Tissue
  • 08:31Results: Transurethral Catheterization to Induce Urinary Tract Infections
  • 09:57Conclusion

Summary

Automatic Translation

Automatic Translation

建立的模型, 经尿道小鼠导尿, 允许研究膀胱疾病, 包括泌尿道感染, 但只能在女性进行。一个新的男性经尿道灌注的模式, 在这里提出, 将使研究在一个地区的特点是强的临床和流行病学差异的性别。

Tags

Urinary Tract InfectionSmall Animal ModelTransurethral CatheterizationMale And Female MiceMucosal ImmunologyUropathogenic E. ColiInoculumBladder Instillation

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