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Cancer Research
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开发和维护的临床前患者来源的肿瘤异种移植模型为新的抗癌疗法的调查
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Cancer Research
Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
Please note that all translations are automatically generated.
Click here for the English version.
开发和维护的临床前患者来源的肿瘤异种移植模型为新的抗癌疗法的调查
DOI:
10.3791/54393-v
•
09:29 min
•
September 30, 2016
•
Stacey Bagby
,
Wells A. Messersmith
,
Todd M. Pitts
,
Anna Capasso
,
Marileila Varella-Garcia
,
Peter J. Klauck
,
Jihye Kim
,
Aik-Choon Tan
,
S. Gail Eckhardt
,
John J. Tentler
,
John Arcaroli
1
Medicine
,
University of Colorado Denver Anschutz Medical Campus
Chapters
00:05
Title
01:04
Blood and Tumor Sample Preparation
03:46
Patient-derived Tumor Xenograft (PDTX) Injection, Bank Maintenance, and Developmental Therapeutics
06:40
Results: PDTX Model Characterization
08:05
Conclusion
Summary
Automatic Translation
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Automatic Translation
在皮下临床前模型利用患者来源的肿瘤是研究新的治疗方法,预测生物标志物的发现,以及耐药性途径的有效性的好方法。这种模式,在药物开发过程中,在事先确定了许多新的抗癌疗法的命运临床研究至关重要。
Tags
Patient-derived Tumor Xenograft
PDX Model
Anti-cancer Therapies
Preclinical Research
Tumor Heterogeneity
Biomarker Discovery
Drug Resistance
Tumor Implantation
Cryopreservation
Histology
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