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The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice
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JoVE Journal Behavior
The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice

The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice

DOI:
10.3791/51944-v

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09:15 min

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February 04, 2015

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, , , , ,
1Department of Pharmacology,University of Texas Health Science Center at San Antonio, 2Audie L. Murphy VA Hospital,South Texas Veteran’s Health Care System

Chapters

  • 00:05Title
  • 01:52Handling and Food Restriction
  • 02:55Acclimation
  • 03:54Training
  • 04:56Testing
  • 06:54Results: Representative Attention Set Shift Task (AST) Performance
  • 08:26Conclusion

Summary

Automatic Translation

Automatic Translation

The goal of this protocol is to perform a behavioral assay such as the attentional set shifting task (AST) to assess prefrontal cortex-mediated cognitive flexibility in mice.

Tags

Cognitive FlexibilityAttentional Set Shifting TaskPrefrontal CortexCognitive ImpairmentNeuropsychiatric DisordersNeurodevelopmental DisordersDepressionPTSDSchizophreniaAutismCognitive FunctionPreclinical Behavioral AssaysMouse ModelsFace ValidityConstruct ValidityPredictive Validity

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