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Journal
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Immunology and Infection
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淋巴免疫治疗和疫苗接种小鼠
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
Intralymphatic Immunotherapy and Vaccination in Mice
Please note that all translations are automatically generated.
Click here for the English version.
淋巴免疫治疗和疫苗接种小鼠
DOI:
10.3791/51031-v
•
07:33 min
•
February 02, 2014
•
Pål Johansen
,
Thomas M. Kündig
1
Department of Dermatology
,
University Hospital Zurich
Chapters
00:05
Title
01:17
Surgical Incision of the Inguinal Area of the Mouse
02:37
Intralymphatic Injection
03:20
Closing the Incision and Post-operative Care
04:56
Results: Advantage of Intralymphatic Vaccinations
07:11
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
预防性和治疗性疫苗往往不能刺激强烈的免疫反应,由于疫苗的周向引流淋巴结细胞和免疫细胞的参与因而不佳。通过直接注射疫苗到淋巴结的,所谓的淋巴内注射,疫苗的有效性,可以大大地改善和疫苗的剂量可以减少。
Tags
Intralymphatic Immunotherapy
Intralymphatic Vaccination
Lymph Node Injection
Lymph Node Targeting
Vaccine Delivery
Immune Response Enhancement
Subcutaneous Vaccination
Intramuscular Vaccination
Antigen Presentation
Lymphocyte Activation
Vaccine Microenvironment
Cytokines
Plasmid DNA
RNA
Peptide
Protein
Particles
Bacteria
Adjuvants
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