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大鼠建立压力超负荷心肌肥厚模型在升主动脉缩窄
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Ascending Aortic Constriction in Rats for Creation of Pressure Overload Cardiac Hypertrophy Model
Please note that all translations are automatically generated.
Click here for the English version.
大鼠建立压力超负荷心肌肥厚模型在升主动脉缩窄
DOI:
10.3791/50983-v
•
10:18 min
•
June 29, 2014
•
Ajith Kumar GS*
1
,
Binil Raj*
1
,
Santhosh Kumar S
,
Sanjay G
,
Chandrasekharan Cheranellore Kartha
1
Cardio Vascular Disease Biology
,
Rajiv Gandhi Centre for Biotechnology
,
2
Animal Research Facility
,
Rajiv Gandhi Centre for Biotechnology
,
3
Cardiology Department
,
Sree Chitra Tirunal Institute for Medical Sciences & Technology
Chapters
00:00
Title
00:06
Introduction
02:30
Pre-Operative Care and Anesthesia
02:43
Preparation of the Surgical Site
03:22
Tracheal Intubation in Rat
04:05
Constriction of Ascending Aorta
07:05
Post-operative Care
07:58
Confirmation of Successful Constriction of Ascending Aorta
08:14
Representative Results
09:21
Conclusion
Summary
Automatic Translation
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Automatic Translation
我们描述了使用一个小的金属夹子由升主动脉缩窄建立压力负荷和左心室肥厚大鼠一个逐步的过程。该模型被广泛用于心肌肥厚过程中学习重塑变化,物色及评估策略,这种变化的回归。
Tags
Ascending Aortic Constriction
Pressure Overload
Cardiac Hypertrophy
Heart Failure
Surgical Model
Rats
Trachea Intubation
Aorta Constriction
Doppler-echocardiography
Cardiac Remodeling
Contractile Properties
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