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Journal
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Immunology and Infection
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使用黑色素瘤和鳞状癌干细胞生成新型支气干细胞疫苗
JoVE Journal
Immunology and Infection
This content is Free Access.
JoVE Journal
Immunology and Infection
Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
Please note that all translations are automatically generated.
Click here for the English version.
使用黑色素瘤和鳞状癌干细胞生成新型支气干细胞疫苗
DOI:
10.3791/50561-v
•
12:43 min
•
January 06, 2014
•
Qiao Li
,
Lin Lu
,
Huimin Tao
,
Carolyn Xue
,
Seagal Teitz-Tennenbaum
,
John H. Owen
,
Jeffrey S Moyer
,
Mark E.P. Prince
,
Alfred E. Chang
,
Max S. Wicha
1
Department of Surgery
,
University of Michigan
,
2
Department of Internal Medicine
,
University of Michigan
,
3
Department of Otolaryngology
,
University of Michigan
Chapters
00:05
Title
02:12
ALDEFLUOR Staining
04:45
Preparation of Cancer Stem Cell Lysate-pulsed Dendritic Cell (CSC-TPDC) Vaccine
07:11
Vaccination and Evaluation of the Efficacy
09:07
Results: CSC-TPDC Vaccination Significantly Inhibits Murine Tumor Growth Activity
12:07
Conclusion
Summary
Automatic Translation
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Automatic Translation
在合成免疫能力宿主中评估,基于癌症干细胞 (CSC) 的树突状细胞 (DC) 疫苗的抗肿瘤免疫力明显高于使用异质散装肿瘤细胞脉冲的传统 DC 疫苗。
Tags
Cancer Stem Cells
Dendritic Cell Vaccine
Melanoma
Squamous Cancer
ALDH
Antitumor Immunity
IFN-γ
GM-CSF
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